Products\ GPU Rack Servers

AMD EPYC™ 9004 single-processor 2U GPU server that supports four dual-slot GPUs, liquid cooling solution, up to 12 DIMM, 8 PCIe 5.0 slots, six NVMe, OCP 3.0 and ASMB11-iKVM

Accelerate performance for HPC and AI workloads

Four dual-slot GPU compute in 2U

ESC4000A-E12 is an AMD EPYC™ 9004 single-socket server built for the demands of enterprise AI infrastructure to deliver unprecedented performance with industry-leading GPUs, faster GPU interconnect and higher-bandwidth fabric, and supports up to four dual-slot active or passive GPUs scalable configuration with a choice of NVIDIA NVLink® Bridge or AMD Infinity Fabric™ Link to enable scaling of performance with increased bandwidth — ready to match your AI and HPC workloads.


  • Powerful performance: Powered by AMD EPYC 9004 processors with 128 Zen 4c cores, 12-channel, up to 4800 MHz DDR5 and support for a maximum TDP of up to 400 watts per socket
  • AI and HPC workloads ready: Up to four dual-slot active or passive GPUs, NVIDIA NVLink® bridge, and NVIDIA Bluefield DPU support to enable performance scaling
  • Power-efficient system design: Independent CPU and GPU airflow tunnels for thermal optimization and support for up to two 2600W Titanium redundant power supplies for uninterrupted operation
  • Comprehensive cooling solutions: Designed for both liquid cooling and enhanced air cooling based on CPU TDP for versatile workloads
  • Scale-up storage and expansion design: A total of six bays in combination of Tri-Mode NVMe/SATA/SAS drives on the front panel and eight PCIe 5.0 slots for higher bandwidth and system upgrade
  • Flexible networking module design: Optional OCP 3.0 module with PCIe 5.0 slot in rear panel for faster connectivity
  • Enhanced IT-infrastructure management: ASUS ASMB11-iKVM remote control with ASPEED AST2600, ASUS Control Center IT management software and hardware-level Root-of-Trust solution


Processor / System Bus

1 x Socket SP5 (LGA 6096)
AMD EPYC™ 9004 series (up to 400W)
4th Generation AMD EPYC Processorswith AMD 3D V-Cache technology


Total Slots : 12 (12-channel)
Capacity : Maximum up to 3TB RDIMM
Memory Type :
DDR5 4800/4400 RDIMM/RDIMM 3DS
Memory Size :
64GB, 32GB, 16GB RDIMM
256GB, 128GB  3DS RDIMM
* Refer to support page for more information

Expansion Slots

-4 x PCIe x16 slots (Gen5 x16 link, FH, FL) for dual-slot GPU cards or
8 x PCIe x16 slots (Gen5 x8 link, FH,FL) for single-slot GPU cards

-1 x PCIe x16 slots (Gen5 x16 link, FH, HL)
-1 x PCIe x16 slot (Gen5 x16/x8 link, FH, HL) or OCP socket option or M.2 riser module
-1 x PCIe x8 slot (Gen5 x0/x8 link, LP, HL)

Front: 1 x PCIe x8 slot (Gen5 x8 link, LP, HL) Only for SKU1


2 x 2.5” & 4 x 3.5“ Hot-swap Storage Bays

2 x 2.5” SATA/SAS*/NVMe +
2 x 3.5” SATA/SAS*/NVMe + 2 x 3.5” SATA/SAS*

SKU2: Build to order
2 x 2.5” SATA/SAS*/NVMe +
4 x 3.5” SATA/SAS*/NVMe (Occupy 1 x PCIe x8 link )

Optional: 1 x M.2 with riser module

*RAID card is required to support SAS hard drives
**For SKU1 additional 2 x NVMe support required a RAID card.

Front I/O Ports

1 x Q-code/port-80 LED
4 x USB 3.2 Gen1 ports

Rear I/O Ports

2 x USB 3.2 Gen1 ports
2 x Gigabit LAN ports 
1 x MAnagement port 
1 x VGA port

Power Supply

1+1 Redundant 2600W 80 PLUS Titanium CRPS-R Power Supply