ASUS ESC4000-E11

Products\ GPU Rack Servers

2U dual-socket GPU server powered by 5th Gen Intel Xeon Scalable processors that supports four dual-slot GPUs, liquid cooling solution, 16 DIMM, six NVMe, two 2600W Titanium power supplies and ASUS ASMB11-iKVM

Accelerate performance for HPC and AI workloads

Four dual-slot GPU compute in 2U

ESC4000-E11 is a dual-socket server powered by 5th Gen Intel Xeon Scalable processors and built for the demands of enterprise AI infrastructure to deliver unprecedented performance with industry-leading GPUs, faster GPU interconnect and higher-bandwidth fabric, and supports up to four dual-slot active or passive GPUs scalable configuration with a choice of NVIDIA NVLink® Bridge to enable scaling of performance with increased bandwidth — ready to match your AI and HPC workloads.


  • Powerful performance: Powered by 5th Gen Intel® Xeon® Scalable processors unleash up to 21%-greater general-purpose performance per watt, significantly improving AI inference and training
  • AI and HPC workloads ready: Up to four dual-slot active or passive GPUs, NVIDIA NVLink® bridge, and NVIDIA Bluefield DPU support to enable performance scaling
  • Power-efficient system design: Independent CPU and GPU airflow tunnels for thermal optimization and support for up to two 2600W Titanium redundant power supplies for uninterrupted operation
  • Comprehensive cooling solutions: Designed for both liquid cooling and enhanced air cooling based on CPU TDP for versatile workloads
  • Scale-up storage and expansion design: A total of six bays in combination of Tri-Mode NVMe/SATA/SAS drives on the front panel and 10 PCIe 5.0 slots for higher bandwidth and system upgrade
  • Flexible networking module design: PCIe 5.0 slot in rear panel for faster connectivity
  • Enhanced IT-infrastructure management: ASUS ASMB11-iKVM remote control with ASPEED AST2600, ASUS Control Center IT management software and hardware-level Root-of-Trust solution


Processor / System Bus

2 x Socket

4th Gen Intel® Xeon® Scalable processors (Up to 350W)
5th Gen Intel® Xeon® Scalable processors (Up to 350W)

Core Logic

Intel® C741 Chipset


Total Slots:
16 (8 channels per CPU, 8 DIMM per CPU)
Maximum up to 4TB per CPU socket
Memory Type:
4th: DDR5 4800 MHz RDIMM/3DS RDIMM (1DPC)
5th: DDR5 5600/4800 MHz RDIMM/3DS RDIMM (1DPC)
512GB, 256GB, 128GB Intel® Optane™ persistent memory 300 series

Expansion Slots

4 x PCIe x16 slots (Gen5 x16 link, FH, FL) for dual-slot GPU cards or
8 x PCIe x16 slots (Gen5 x8 link, FH,FL) for single-slot GPU cards
-2 x PCIe x16 slots (Gen5 x16 link, FH, HL)
1 x PCIe x8 slot (Gen4 x8 link, LP, HL)


2 x 2.5” & 4 x 3.5“ Hot-swap Storage Bays
2 x 2.5” SATA/SAS*/NVMe +
2 x 3.5” SATA/SAS*/NVMe + 2 x 3.5” SATA/SAS*
SKU2: Build to order
2 x 2.5” SATA/SAS*/NVMe +
4 x 3.5” SATA/SAS*/NVMe (Occupy 1 x PCIe x8 link )
*SAS support required a HBA/RAID card.
**For SKU1 additional 2 x NVMe support required a RAID card.

1 x M.2 socket (Gen3 x4 link PCIe mode, up to 2280)

Front I/O Ports

4 x USB 3.2 Gen1 ports

Rear I/O Ports

2 x USB 3.2 Gen1 ports
2 x Gigabit LAN ports (RJ45)
1 x MAnagement port (RJ45)
1 x VGA port

Power Supply

1+1 Redundant 2600W 80 PLUS Titanium CRPS-R Power Supply