ASUS ESC4000-E10

Products\ GPU Rack Servers

2U GPU server powered by dual-socket 3rd Gen Intel Xeon Scalable processors that supports up to 16 DIMM, four dual-slot GPU, 4 M.2, eight NVMe (by SKU), total eleven PCIe 4.0 slots, one OCP 3.0 (by SKU) and ASUS ASMB10-iKVM.

GPU and FPGA support

ESC4000-E10 features a powerful GPU architecture that supports up to four double-slot or eight single-slot GPUs* in a 2U chassis, including NVIDIA® A100 or Quadro®, plus features NVIDIA NVLink® Bridge to enable scaling of performance in order to meet the demands of AI and high-performance computing, and to securely run workloads in virtualization environments.

ESC4000-E10 is also a Xilinx Alveo-qualified server to provide optimized acceleration for workloads across cloud and on-premises data centers, and for hybrid cloud environments in financial computing, machine learning, computational storage, and data search and analytics.


  • Powered by dual-socket 3rd Gen Intel Scalable processors, with 16 DIMMs and support for a maximum TDP of up to 205 watts per socket
  • GPU-optimized design allows four dual-slot GPUs for AI workloads
  • Up to eight all-flash NVMe and eight SATA/SAS drives on front panel to enable extensive storage and high-throughput performance
  • Up to eleven PCIe® 4.0 slots to enable higher bandwidth and improved data-transfer rates
  • Flexible air- solution to achieve lower power-usage effectiveness (PUE) and optimized TCO for data centers
  • Onboard ASUS ASMB10-iKVM for out-of-band management with ASPEED AST2600 controller
  • Integrated PFR FPGA as the platform Root-of-Trust solution for firmware resiliency
  • High power efficiency with redundant 2200W or 1600W 80 Plus® Platinum power supplies
  • Two hot-plug, hot-swap fans design for fully redundancy protection and thermal efficiency


Processor / System Bus

2 x Socket P+ (LGA 4189)
3rd Gen Intel® Xeon® Scalable Processors Family(205W)

Core Logic

Intel® PCH C621A


Total Slots :
16 (8-channel, 1DPC)
Capacity :
Up to 4,096GB DIMM
Up to 6,144GB DIMM+PMem (200 series)
Memory Type :
Memory Size :
256GB, 128GB, 64GB, 32GB, 16GB
512GB, 256GB, 128GB Intel® Optane™ DC Persistent Memory 200 Series (DCPMM)

Expansion Slots

– 4 x PCIe x16 slots (Gen4 x16 link, FH,FL) for dual-slot GPU cards or
   8 x PCIe x16 slots (Gen4 x8 link, FH,FL) for single-slot GPU cards*
– 2 x PCIe x16 slots (Gen4 x16 link, LP,HL)
– SKU-1:
1 x PCIe x8 slot (Gen4 x8 link, LP,HL)
4 x M.2 sockets (Gen4 x4 link, up to 22110 module)
– SKU-2:
1 x PCIe x8 slot (Gen4 x8 link, LP,HL)
1 x OCP3.0 slot (Gen4 x16 link)
– SKU-3:
8 x 3.5” NVMe support


Storage Controller :
Intel® PCH C621A

Optional kits Controller :
ASUS PIKE II 3008-8i 8-port SAS 12G HBA card
ASUS PIKE II 3108-8i 8-port SAS 12G RAID card

8 x 3.5″ Hot-swap Storage Bays
(SKU-1 & SKU-2 Backplane Supports 6 x SATA/SAS + 2 x SATA/SAS/NVMe Devices**)
(SKU-3 Backplane Supports 8 x SATA/SAS/NVMe Devices)
1 x M.2 socket (Gen3 x4 link or SATA mode, up to 2280 on-motherboard)

Front I/O Ports

4 x USB 3.2 Gen1 ports

Rear I/O Ports

2 x USB 3.2 Gen1 ports
1 x VGA port
2 x 1GbE LAN ports (RJ45)
1 x Management port (RJ45)

Power Supply

1+1 Redundant 1600W 80 PLUS Platinum Power Supply C-14 power inlet
Rating: 100-127Vac/200-240Vac,12.9A/9.5A,50-60Hz

1+1 Redundant 2200W 80 PLUS TITANIUM Power Supply C-20 power inlet
Rating: 100-127Vac/200-240Vac,14A/12.6A,47-63Hz